Designed and patented by Colorectal Surgeons10Includes: Reusable Anal Applicators (5 each), Reusable Dosing Syringes (5 each), Dosing Jar (1 each), Medication Tube-to-Syringe Adapter (1 each)10Precise delivery to anal canal reduces sphincter spasm for greater pain relief10Made in the USA by Surgin Medical. Does not include Medication10